We dare to think differently.

Cancer Grand Challenges is a global research initiative that identifies the toughest challenges in cancer research. With awards of up to $25m, it empowers global, interdisciplinary teams to take them on.

Founded by Cancer Research and National Cancer Institute

New challenges

The newest set of challenges, now open for Expressions of Interest.

Explore the new challenges

Active challenges

The challenges currently being addressed by our funded teams.

Explore our active challenges

Concluded challenges

The challenges we’ve set where teams’ funding has come to an end.

Explore our concluded challenges

Unfunded challenges

The challenges we’ve set that haven't been addressed by a funded team.

Explore our unfunded challenges

Our mission

Learn more about our mission to solve cancer’s toughest challenges.

Professor Judy Garber at a Scientific Committee meeting, to set our 2023 challenges

Our process

Find out how we identify the most complex problems in cancer research, and then commit to funding teams to tackle them.

Spatial proteomics analysis of human pancreas tissue

Impact

Explore how our first round of funded teams pushed the boundaries of cancer research and delivered progress against their challenges.

Ryan Schoenfeld at Mark Foundation symposium

Partners and donors

Meet our global network of partners and individual donors whose support is helping us to transform the landscape of cancer research.

Scientific Committee

Meet our Scientific Committee, a group of world-leading scientists who provide input at every stage of the process, from setting challenges to supporting funded teams.

News

Explore the latest stories from Cancer Grand Challenges and our community.