A new era of discovery
We dare the very best to come together, think differently and make progress against cancer's toughest challenges.

Who will solve cancer’s most complex challenges?
In June 2022 we announced 4 new teams receiving $100m to take on some of cancer's toughest challenges.
We have now launched a global conversation in late 2022 to identify the next round of challenges that will be open for applications in March 2023.
Successful teams each receive up to £20m ($25m) to carry out team science on a global scale.
Catalysing a step change in cancer research
Every two years we work with the global research community to identify some of the most complex problems in cancer research – those which, if solved, could make the biggest difference to progress.
Together with our partners, we convene workshops around the world, consulting with researchers, people affected by cancer and other research organisations. We also invite the submission of ideas online.
This rigorous process captures a breadth of ideas that are interrogated by the Cancer Grand Challenges Scientific Committee – a selection of the world’s most eminent scientists. Cancer Research UK and the National Cancer Institute make the final decision on which challenges should be posed to the research community.