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Our mission

Harnessing the power of discovery to tackle cancer’s most complex challenges.

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A new era of discovery

What will it take to transform our understanding of cancer? To push boundaries? And to move beyond incremental improvements in how we prevent, diagnose and treat cancer?

It’s within our reach. But first, we need to tackle many of the most intractable problems standing in the way of progress.

Founded by:

Cancer Research UK
National Cancer Institute

Amplifying potential

Cancer Grand Challenges is a global funding initiative founded in 2020 by the two largest funders of cancer research in the world: Cancer Research UK and the National Cancer Institute in the US.

This partnership builds on the success of Cancer Research UK’s Grand Challenge, launched in 2015 and currently supporting 7 multidisciplinary teams across 9 countries.

By daring global teams of multidisciplinary researchers to come together and think differently, we can find bold new solutions to challenges which have confounded scientists for many years.

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Building a global network

To drive a step change in cancer research, we need to be ambitious. The challenges blocking our progress demand global team science and funding on an unprecedented scale: we need to rethink our approach and usher in a new era of discovery.

With collective support from global funders, partners and philanthropists who share our aspirations, we have the power to create change. Together we can galvanise the world’s scientific community – freeing them from constraints to inspire their scientific creativity.

We’ve witnessed great progress. But complex challenges still stand. It’s time to come together, think differently and create change.