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Unfunded challenges

Challenges which don't have a funded team working to tackle them

Alongside our active and concluded challenges, these challenges were identified by our Scientific Committee and founders as being some of the most urgent in cancer research. 

While they were posed to the research community, ultimately, no team was funded to tackle them. They're not open for applications.

Explore our unfunded challenges below.

2023

Ageing and cancer icon
Challenge: Decipher the functional basis underlying the association between ageing somatic tissues and cancer
Cancer cell plasticity icon
Challenge: Understand cancer cell plasticity and its contribution to the development of pan-therapeutic resistance in cancer.

2020

Ecigarettes icon
Challenge: Determine the potential benefits and risks of e-cigarette use
Macromolecules challenge icon
Challenge: Systemically deliver macromolecules to intracellular targets for therapeutic benefit in cancer
Senescence icon
Challenge: Understand and exploit senescence to improve cancer treatment

2017

Artificial intelligence icon
Challenge: Detect cancer earlier by interrogating medical and non-medical data sets using machine and deep-learning
Dormancy icon
Challenge: Identify and target tumour cells that remain dormant for many years after seemingly effective treatment
Treatment regimens
Challenge: Define mechanistic rules for combinatorial treatments to overcome resistance and avoid toxicity
Tumour vaccinology icon
Challenge: Create novel tumour vaccinology approaches that establish or enhance successful immune responses beyond what is revealed by current checkpoint therapy

2015

Targeting Myc challenge icon
Challenge: Develop innovative approaches to target the cancer supercontroller Myc

Explore other challenges

PRECISION DCIS challenge

Learn more about our concluded challenges, which were being tackled by teams whose funding period has now come to an end.