News & Insight

News
Announcing the global teams that have been shortlisted for a Cancer Grand Challenges award
Announcing the shortlist for the Cancer Grand Challenges awards. 12 teams competing for up to $25m each in funding.
Today, we are excited to reveal the 12 shortlisted teams who are in with a chance of securing up to $25m in Cancer Grand Challenges funding to make radical progress against some of cancer’s toughest challenges.   In March 2023, we…
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The power of combining mass spectrometry techniques to interrogate the cancer metabolome
New research from the Cancer Grand Challenges Rosetta team shows that metabolic profiling using a variety of mass spectrometry techniques can be used…
People
Introducing new Scientific Committee member, Dr Tom Misteli
We are pleased to welcome Dr Tom Misteli of the National Cancer Institute’s Center for Cancer Research, USA, to the Cancer Grand Challenges…
People
Introducing the new members of the Cancer Grand Challenges Advocacy Panel
We are pleased to welcome seven new members to the Cancer Grand Challenges Advocacy Panel: Yelak Biru, Ivana Cattaneo, Anjee Davies, Joya Harris,…
News
Considering the bigger picture in the treatment of cancer: new findings from the team taking on our Cachexia challenge
New research from the Cancer Grand Challenges CANCAN team finds that a ketogenic diet slows tumour growth but shortens survival by accelerating the…

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David Scott and Dinah Singer
Coverage
AACR Cancer Discovery In Focus: harnessing the power of discovery
In an ‘In Focus’ commentary article for AACR Cancer Discovery, Dr David Scott and Dr Dinah Singer discuss our nine new Cancer Grand Challenges, for which Expressions of Interest are open until 22 June 2023. In March at…
Image of Stefan Hutten alongside the article title - A unique resource for studying DCIS and progression to cancer
News
A unique resource for studying DCIS and progression to cancer
Members of the Cancer Grand Challenges PRECISION team have developed a living biobank of 115 patient-derived Mouse-INtraDuctal (MIND) ductal carcinoma in situ (DCIS) models and used them to identify risk factors…
"NexTGen represents crucial and overdue work” Sara Wakeling, NexTGen team advocate and CEO and co-founder of Alice's Arc
News
Targeting vulnerabilities of childhood cancers
Cancer is the second leading cause of death among children and adolescents worldwide. Yet, despite progress in understanding the biology of many childhood cancers, treatments, particularly for solid tumours, have…
2022/23 Discover: A year of scientific creativity
News
Discover: a year of scientific creativity 2023
Today we launch Discover: a year of scientific creativity – our annual progress magazine We are excited to launch our annual progress magazine, Discover: a year of scientific creativity. Discover celebrates how the…
"Being a part of Cancer Grand Challenges is truly a unique experience" Amy Brigham and Women's Hospital and team SPECIFICANCER
Blog
"Being a part of Cancer Grand Challenges is truly a unique experience"
In November 2022, Cancer Grand Challenges held its first in-person Future Leaders Conference in Barcelona, providing an opportunity for early-career researchers worldwide to connect, network and spark new scientific…
"I really believe the way we enable research through Cancer Grand Challenges will ultimately make a difference for people with cancer" Gemma Balmer-Kemp, head of research, Cancer Grand Challenges
Blog
The multifaceted approach of Cancer Grand Challenges research
Cancer Grand Challenges research covers a broad spectrum of areas and disciplines, with teams generating novel insights at each stage of the research pipeline. Here, Gemma Balmer-Kemp, head of research at Cancer Grand…
Spotlight on the new Cancer Grand Challenges teams
Blog
Spotlight on the new Cancer Grand Challenges teams
Cancer Grand Challenges awarded grants to four teams –CANCAN, PROMINENT, eDyNAmiC and NexTGen – in its third round of funding in 2022. Charles Swanton, a member of the Cancer Grand Challenges Scientific Committee,…
eDyNAmiC
News
Novel insights into the role of ecDNA in the cancerous transition of Barrett's oesophagus
Lorenzo de la Rica, Research Programme Manager at Cancer Grand Challenges, provides his insights on the importance of the latest paper from the Cancer Grand Challenges eDyNAmiC team, tackling the extrachromosomal DNA…
A scanning electron micrograph of cancer cells in the intestine STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY
Coverage
Cancer mystery as cases rise among younger people around the world
When it comes to cancer research, we regularly hear good news about the number of people benefiting from advances in treatment. But there is one bad news story about the condition that gets little attention. For three…