News & Insight

News
Changing the narrative around ductal carcinoma in situ and breast cancer risk
A radiographer examining a mammogram image
New findings from the Cancer Grand Challenges PRECISION team this Breast Cancer Awareness Month show that breast cancer development from DCIS is a rare event and emphasise the urgent need for accurate prognostic markers to combat DCIS…
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News
Major new scientific partnership between the UK and France to tackle cancer’s toughest challenges
Today we’re announcing a major new €10m (£8.6m) partnership between Cancer Research UK and France’s Institut National Du Cancer (INCa) to help fund…
News
Announcing the global teams that have been shortlisted for a Cancer Grand Challenges award
Today, we are excited to reveal the 12 shortlisted teams who are in with a chance of securing up to $25m in Cancer Grand Challenges funding to make…
News
The power of combining mass spectrometry techniques to interrogate the cancer metabolome
New research from the Cancer Grand Challenges Rosetta team shows that metabolic profiling using a variety of mass spectrometry techniques can be used…
People
Introducing new Scientific Committee member, Dr Tom Misteli
We are pleased to welcome Dr Tom Misteli of the National Cancer Institute’s Center for Cancer Research, USA, to the Cancer Grand Challenges…

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eDyNAmiC
News
Novel insights into the role of ecDNA in the cancerous transition of Barrett's oesophagus
Lorenzo de la Rica, Research Programme Manager at Cancer Grand Challenges, provides his insights on the importance of the latest paper from the Cancer Grand Challenges eDyNAmiC team, tackling the extrachromosomal DNA…
A scanning electron micrograph of cancer cells in the intestine STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY
Coverage
Cancer mystery as cases rise among younger people around the world
When it comes to cancer research, we regularly hear good news about the number of people benefiting from advances in treatment. But there is one bad news story about the condition that gets little attention. For three…
Nine new challenges
Blog
Announcing nine of cancer’s toughest challenges with up to $25m funding for global research teams
Today we announce nine new Cancer Grand Challenges, for which Expressions of Interest are now open. These are the obstacles that continue to impede progress against cancer and that no one scientist, institution or…
CGC new Scientific Committ
Blog
Introducing our new Scientific Committee members
We are pleased to welcome five new members to the Cancer Grand Challenges Scientific Committee: Professor Michael Hall (University of Basel), Professor Sherene Loi (Peter MacCallum Cancer Center), Professor KJ Patel (…
It's been an incredible year of discoveries for Cancer Grand Challenges and we look forward to seeing what 2023 brings
Blog
Team science: 2022 highlights
Lorenzo de la Rica (@LdelaRica) is Research Portfolio Manager at Cancer Grand Challenges In 2022, we have seen our Cancer Grand Challenges (CGC) community grow, with four new teams receiving a total of $100m funding.…
Video
The virtual reality tumour map that could revolutionise cancer treatment
In 2017, the IMAXT team was awarded £20 million by Cancer Grand Challenges, funded by Cancer Research UK. Through the Cancer Grand Challenges initiative, a global team of experts from fields as diverse as medicine,…
Sheona Scales - Head of Research, Cancer Grand Challenges
Blog
A global search for cancer's toughest challenges
We’re leading a global conversation to help shape our next round of funding, inviting the submission of ideas via our Online Ideas Portal from now until 28 November.   Here, Sheona Scales, Head of Research at Cancer…
DNA code
News
A new tool to probe mutational signatures – and the long-sought-after link between tobacco and bladder cancer
How a suite of advanced machine learning algorithms is finding new cancer-causing patterns of DNA damage Cancer Grand Challenges researchers and collaborators have identified four new mutational signatures, including a…
Image of Sara Wakeling and her daughter, Alice
Blog
"Our team’s work has hope written all over it”
Advocacy plays a major role in Cancer Grand Challenges. The team taking on our Solid Tumours in Children challenge includes six advocates, representing the voice of children and families affected by solid cancers and…