News & Insight

20 October 2021
News
New findings, old ideas: reviving a decades old view on the causes of cancer
Mutographs
Surprising discoveries from the Mutographs team challenge the classical view that all carcinogens directly cause mutations and suggest that non-mutagenic agents play a greater role in tumour promotion than originally thought. This story…

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20 October 2021
Today we launch Discover: a year of scientific creativity – our annual progress magazine showcasing the power of global team science.  Discover …
News
20 October 2021
The SPECIFICANCER team delves deeper into the biological laws that govern tissue specificity in cancer and reveals intricate webs of genetic…
News
20 October 2021
A new expansion sequencing toolbox and analysis platform from the IMAXT team reveals hidden truths in biology by creating detailed nanoscale-…
News
20 October 2021
A deeper understanding of the metabolic changes during tumour development could radically change clinical decision-making and unlock opportunities to…

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Our keynote speaker @UriAlonWeizmann spoke (and sang) about how a career in research is not always as glamourous an… https://t.co/JpblYOWvTO Thu Oct 14 15:21:40 +0000 2021

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Video
Nearly 170 diverse, global teams submitted bold ideas outlining how they would solve some of cancer’s toughest challenges. Today, we reveal the 11 teams selected to compete for a share of £80m.   We were delighted to…
21 June 2021
News
APC is one of the most commonly mutated genes in colorectal tumours – but why is it so frequently mutated in this type of cancer compared to others? The answer lies in the way APC-mutant cells compete with their…
3 June 2021
Video
Patient advocate Helen Matthews meets co-investigator Owen Sansom to discuss SPECIFICANCER’s latest findings, how working cross-discipline enables ‘big strides forward’ and the unique, important perspectives brought to…
1 June 2021
News
New findings from the OPTIMISTICC team reveal aspirin’s antibacterial activity against Fusobacterium nucleatum, an oncomicrobe known to drive colorectal cancer.   OPTIMISTICC’s Caitlin Brennan, postdoctoral fellow and…
21 April 2021
News
By distinguishing between people with ductal carcinoma in situ (DCIS) who will develop invasive breast cancer and those who won’t, the Cancer Grand Challenges PRECISION team could spare thousands of women around the…
15 April 2021
Video
Look inside the IMAXT team’s virtual reality lab, ahead of its release later this year, as the team calls for volunteers to help test the software.   A core component of the Cancer Grand Challenges IMAXT programme,…
13 April 2021
News
Findings from the OPTIMISTICC team point towards a global microbiome signature for colorectal cancer that could help improve the way we detect the disease. Colorectal cancer is the third most common cancer in the world…
31 March 2021
Blog
In October, we posed 9 new challenges to the research community, each with the potential to change the way we think about cancer. Through our blog series, members of our Cancer Grand Challenges Scientific Committee…
30 March 2021
Video
We recently held a webinar with the American Association for Cancer Research (AACR) providing an overview of the Cancer Grand Challenges partnership between Cancer Research UK and the US National Cancer Institute. …
30 March 2021