News & Insight

News
Five new teams selected to take on cancer’s toughest challenges
Announcing five new global Cancer Grand Challenges teams. Each team will be awarded up to $25m over five years to take on cancer's toughest problems.
Today we’re excited to announce the five new global teams that have been selected to each receive up to $25m in Cancer Grand Challenges funding over five years to take on four of cancer’s toughest challenges. In March 2023, we announced…
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Blog
Embedding patient advocacy within a discovery science initiative
As we look towards announcing our new teams on 6 March, we reflect with former members of the Cancer Grand Challenges Advocacy Panel on the role the…
Blog
A holistic approach to cancer research: bringing future research leaders together with patient advocates
Last month we held our annual Future Leaders Conference in Lisbon. As well as being a time for early career researchers from across our funded teams…
News
Changing the narrative around ductal carcinoma in situ and breast cancer risk
New findings from the Cancer Grand Challenges PRECISION team this Breast Cancer Awareness Month show that breast cancer development from DCIS is a…
News
Major new scientific partnership between the UK and France to tackle cancer’s toughest challenges
Today we’re announcing a major new €10m (£8.6m) partnership between Cancer Research UK and France’s Institut National Du Cancer (INCa) to help fund…

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Josephine Bunch photo
Blog
A powerful lens into tumour metabolism
Josephine Bunch reflects on a new way to map cancer.  In taking on our 3D Tumour Mapping challenge, the Cancer Grand Challenges Rosetta team has curated a suite of mass spectrometry imaging (MSI) techniques that can…
Image card of Peter Campbell
Blog
Cancer’s secrets uncovered from non-cancerous tissue
What can studying non-cancerous tissue from people with cancer teach us about a tumour? Dr Peter Campbell (Sanger Institute, Cambridge, UK), co-investigator of the team taking on our Unusual Mutation Patterns challenge…
This photograph depicted an Enteric Diseases Laboratory Branch (EDLB) public health scientist, preparing bacteria for a DNA fingerprinting test
News
Study suggests C. difficile drives some colorectal cancers
Common infection could be one driver of colorectal cancer rise in younger adults, according to findings from members of the team taking on our Microbiome challenge.   Data collected by researchers at the Johns Hopkins…
NexTGen at summit
Blog
Bringing next-generation CAR T-cell therapies to children with solid cancers
On 16 June 2022, we announced 4 new Cancer Grand Challenges teams taking on some of the toughest challenges in cancer research. Here, meet the NexTGen team receiving $25m to take on the Solid Tumors in Children…
CANCAN team at Cancer Grand Challenges summit
Blog
The Cancer Cachexia Action Network - meet the team taking on the Cachexia challenge
On 16 June 2022, we announced four new Cancer Grand Challenges teams taking on some of the toughest challenges in cancer research. Here, meet the CANCAN team receiving $25m to take on the Cachexia challenge.  Many…
PROMINENT team at the Cancer Grand Challenges summit
Blog
“We want to stop cancer before it even starts” - meet the team taking on the Normal Phenotypes challenge 
On 16 June 2022, we announced four new Cancer Grand Challenges teams taking on some of the toughest challenges in cancer research. Here, meet the PROMINENT team receiving $25m to take on the Normal Phenotypes challenge…
$100m funded - meet the new teams
News
Announcing 4 new teams receiving $100m to take on cancer's toughest challenges
Today we announce the four new teams selected to each receive $25m Cancer Grand Challenges funding to take on some of the toughest challenges in cancer research.   Representing a total investment of $100m, these are…
Microarray
News
A comprehensive map of cancer genomes and chromosomal changes
Cancer Grand Challenges scientists and collaborators have created the first map of the major chromosomal changes that occur during cancer. This information could help physicians better understand how individual tumours…
Precision dcis
News
A step closer to avoiding overtreatment in people with DCIS
Today, the team taking on our Lethal vs. Non-Lethal challenge shared new findings that could change management and treatment for people with ductal carcinoma in situ (DCIS).   To find out more about the clinical…