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Five new teams selected to take on cancer’s toughest challenges
Announcing five new global Cancer Grand Challenges teams. Each team will be awarded up to $25m over five years to take on cancer's toughest problems.
Today we’re excited to announce the five new global teams that have been selected to each receive up to $25m in Cancer Grand Challenges funding over five years to take on four of cancer’s toughest challenges. In March 2023, we announced…

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As we look towards announcing our new teams on 6 March, we reflect with former members of the Cancer Grand Challenges Advocacy Panel on the role the…
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Last month we held our annual Future Leaders Conference in Lisbon. As well as being a time for early career researchers from across our funded teams…
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New findings from the Cancer Grand Challenges PRECISION team this Breast Cancer Awareness Month show that breast cancer development from DCIS is a…
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Today we’re announcing a major new €10m (£8.6m) partnership between Cancer Research UK and France’s Institut National Du Cancer (INCa) to help fund…

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How do tumours avoid attack from the immune system? For some head and neck cancers, the answer lies on the short, p, arm of chromosome 9 – findings from the Cancer Grand Challenges SPECIFICANCER team which could lead…
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We (virtually) sat down with John Marioni, new collaborator on the Cancer Grand Challenges IMAXT programme to find out more about his work. John is a senior group leader at the Cancer Research UK Cambridge Institute,…
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OPTIMISTICC’s Cindy Sears is a clinician scientist at Johns Hopkins University School of Medicine and an expert in infectious disease and colorectal cancer. In July, Cindy and the team shared a new mouse model which…
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On the surface, astronomy has little overlap with bioinformatics, mutational analysis and other areas of cancer biology. But, as described by IMAXT’s Nic Walton, an astronomer based at the University of Cambridge, there…
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Sir Mike Stratton, based at the Wellcome Sanger Institute in Cambridge, UK, leads the Cancer Grand Challenges Mutographs team. Mutographs unites genomicists with epidemiologists, building on recent developments in…
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Earlier this year, COSMIC - the world's largest and most comprehensive resource for exploring somatic mutations in cancer - celebrated the curation of its 10 millionth mutation.  PhD student Ellie Dunstone discusses…
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Johanna Joyce is co-investigator of the Cancer Grand Challenges IMAXT team, based in Lausanne, Switzerland.   We caught up with Johanna to learn how diverse, global collaboration is helping to unlock new information…
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Nearly 170 diverse, global teams submitted bold ideas outlining how they would solve some of cancer’s toughest challenges. Today, we reveal the 11 teams selected to compete for a share of £80m.   We were delighted to…
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APC is one of the most commonly mutated genes in colorectal tumours – but why is it so frequently mutated in this type of cancer compared to others? The answer lies in the way APC-mutant cells compete with their…