News & Insight

7 November 2022
Blog
A global search for cancer's toughest challenges
Sheona Scales - Head of Research, Cancer Grand Challenges
We’re leading a global conversation to help shape our next round of funding, inviting the submission of ideas via our Online Ideas Portal from now until 28 November.   Here, Sheona Scales, Head of Research at Cancer Grand Challenges,…
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News
14 October 2022
A new tool to probe mutational signatures – and the long-sought-after link between tobacco and bladder cancer
How a suite of advanced machine learning algorithms is finding new cancer-causing patterns of DNA damage Cancer Grand Challenges researchers and…
Blog
21 September 2022
"Our team’s work has hope written all over it”
Advocacy plays a major role in Cancer Grand Challenges. The team taking on our Solid Tumours in Children challenge includes six advocates,…
News
25 July 2022
Discover: a year of scientific creativity 2022
Today we launch Discover: a year of scientific creativity – our annual progress magazine showcasing the power of global team science.  Discover …
Blog
25 July 2022
An atlas of oesophageal cancer development
From the team taking on our Cancer Causes challenge, a new integrated atlas of the stromal and epithelial interactions that drive cancers associated…

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The deadline to submit your idea for our next round of #CancerGrandChallenges is 28 Nov. So here's some more great… https://t.co/TqdlWHb6BR Thu Nov 17 11:18:50 +0000 2022

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Professor Sir David Lane
Blog
The Challenges: Professor Sir David Lane shares his thoughts on the macromolecules challenge
In October, we posed 9 new challenges to the research community, each with the potential to change the way we think about cancer. Through our new blog series, members of our Cancer Grand Challenges Scientific Committee…
18 November 2020
Cancer Grand Challenges Summit 2020 attendees
Blog
The power of discovery: 7 teams leading the way
With our first Cancer Grand Challenges blog, we reflect on the progress of the 7 teams tackling some of cancer’s toughest challenges.  It started in 2015, with 7 audacious challenges.   Since then, we’ve supported 7…
16 November 2020
9 colour block illustrations of cells
Coverage
Nature Reviews Drug Discovery: addressing cancer’s grand challenges
Read the latest coverage of Cancer Grand Challenges.   “All these ‘challenges’ are actually very interesting and highly worthy of the attention of the cancer research community,” says Robert Weinberg, of the Whitehead…
13 November 2020
Credit: Jeroen Claus (Phospho Biomedical Animation)
News
Metabolic fingerprinting reveals link between dietary fat restriction and therapy response
Research from the Cancer Grand Challenges Rosetta team has identified a potential metabolic weakness in cancer that could be amenable to treatment.   The findings, published in Cell, focused on exploring whether the…
29 October 2020
Bowel cancer cell, CRUK LRI Experimental Histopathology Unit
News
OPTIMISTICC: New connection drives poor outcomes in bowel cancer
Up to 45% of bowel cancers carry a fault in the KRAS gene, detrimentally affecting how a patient will respond to treatment. New results from the OPTIMISTICC team suggest these poor outcomes may be due to the way faulty…
20 October 2020
Lung cancer cell, full credit to LRI EM department.
News
Catalysing new thinking on the development of cancer
Some carcinogens can cause cancer without directly damaging DNA: a new study from the Cancer Grand Challenges Mutographs team challenges a long-held view on the early development of a tumour. For years, research has…
13 October 2020
Barbara Rimer and Jill P. Mesirov
People
New Scientific Committee members announced
The Cancer Grand Challenges Scientific Committee is pleased to welcome two new members: Professor Jill P Mesirov (University of California San Diego School of Medicine) and Professor Barbara K Rimer (University of North…
11 October 2020