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Professor Chris Garcia
Meet Chris, a co-investigator on MATCHMAKERS
Chris Garcia elucidated the structural framework for TCR recognition of pMHC, and pioneered diversity-based approaches to profile and engineer TCR specificity and cross-reactivity in TCR signaling. He has translated these findings to the clinic. For the Grand Challenge, the Garcia lab is focused on developing approaches for simulating TCR-peptide MHC diversity using in vitro evolution approaches.