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Teams

Team science on a global scale

We back world-class, multidisciplinary teams to come together, think differently and make radical progress against cancer.

Breaking boundaries in science

Cancer is a universal challenge, posing tough, complex problems to researchers, clinicians and people living with the disease. Solving these problems demands tenacity, creativity and worldwide collaboration. Our teams rise above the boundaries of geography and discipline to take these challenges on and propel our understanding of cancer to new places.

INVESTMENT
TO DATE:
£130m
TEAMS
FUNDED:
7
INVESTIGATORS AND
COLLABORATORS:
600+
COUNTRIES INVOLVED:
9
Focus:
3D tumour mapping

Can we build a complete picture of the anatomy of a tumour?

By developing the world’s first virtual reality map of cancer – an entirely new way to study a tumour – IMAXT could revolutionise the diagnosis and treatment of people with the disease.
Awarded year 2017
Focus:
Unusual mutation patterns

Discover how unusual patterns of mutation are induced by different cancer-causing events 

It’s a cliché, but prevention really is better than cure. By examining the damaging fingerprints left on our DNA by cancer-causing factors, the Mutographs team hopes to identify unknown causes of cancer to help prevent more people from developing the disease.
Awarded year 2017
Focus:
Microbiota

Improve treatment responses by manipulating the composition and status of the microbiota 

It’s becoming increasingly clear that bowel cancer – the third most common cancer worldwide – is intricately linked to microbes in the gut. By exploring how these microbes drive cancer and influence a person’s response to treatment, the OPTIMISTICC team could transform outcomes for people around the world.
Awarded year 2019
Focus:
Lethal versus non-lethal

Distinguish between lethal cancers that need treating, and non-lethal cancers that don’t 

By distinguishing between people with DCIS who will develop breast cancer and those who won’t, the PRECISION team could spare thousands of women around the world unnecessary treatment, transforming their quality of life.
Awarded year 2017
Focus:
3D tumour mapping

Can we build a complete picture of the anatomy of a tumour?

By developing a map of cancer akin to Google Earth – zooming from the whole tumour right down into individual molecules inside cells – the Rosetta team could transform our understanding of cancer and pioneer more effective cancer treatments.
Awarded year 2017
Focus:
Tissue specificity

Understand why mistakes in certain genes only cause cancer in specific parts of the body  

The past 30 years have identified hundreds of genes that, when mutated, can cause cancer. But the vast majority of these genes only cause cancer in specific parts of the body and not in others – and we don’t know why. By tackling this challenge, SPECIFICANCER could revolutionise our understanding of cancer biology.
Awarded year 2019
Focus:
Cancer causes

Understand how lifestyle factors, such as obesity, cause cancer

Targeting a tumour directly can kickstart its ‘survival mode’, leading to treatment resistance and metastasis. STORMing Cancer’s stealth approach instead targets the cells and tissues surrounding a tumour and could benefit up to 1 in 4 people with cancer around the world.
Awarded year 2019