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Five new teams selected to take on cancer’s toughest challenges
Announcing five new global Cancer Grand Challenges teams. Each team will be awarded up to $25m over five years to take on cancer's toughest problems.
Today we’re excited to announce the five new global teams that have been selected to each receive up to $25m in Cancer Grand Challenges funding over five years to take on four of cancer’s toughest challenges. In March 2023, we announced…

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As we look towards announcing our new teams on 6 March, we reflect with former members of the Cancer Grand Challenges Advocacy Panel on the role the…
Blog
Last month we held our annual Future Leaders Conference in Lisbon. As well as being a time for early career researchers from across our funded teams…
News
New findings from the Cancer Grand Challenges PRECISION team this Breast Cancer Awareness Month show that breast cancer development from DCIS is a…
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Today we’re announcing a major new €10m (£8.6m) partnership between Cancer Research UK and France’s Institut National Du Cancer (INCa) to help fund…

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News
Inflammation coaxes lung epithelial cells to be replaced by those more commonly seen in other organs - a clinically relevant event that can be studied using accurate in vitro models of the human lung. In response to…
Video
Members of the Cancer Grand Challenges Mutographs team challenge the current theory of ageing, revealing that healthy cells can tolerate many more mutations that previously assumed. What causes us to age? A popular…
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A generous gift from industrialist and investor Bjorn Saven has helped to launch our Future Leaders Conference.  In October, we launched our inaugural Future Leaders Conference, powered by a steering committee of PhD…
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Survival for pancreatic cancer remains intractably low, with just 9% of people surviving for 5 years beyond diagnosis. For World Pancreatic Cancer Day 2021, we’re shining a light on much-needed research into the disease…
News
Members of the Cancer Grand Challenges community feature in a new exhibition on cancer research from the Science Museum Group.  Cancer Revolution: Science, Innovation and Hope is the world’s first major exhibition…
Video
A short film from Columbia Cancer Research featuring members of our IMAXT team – co-investigators Simon Tavaré and Owen Harris, and postdoctoral researcher Ignacio Vazquez-Garcia. Learn more about the IMAXT team.…
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The Cancer Grand Challenges Mutographs team has added an unexpected piece to the complex puzzle surrounding the development of oesophageal squamous cell carcinoma (ESCC): no mutational signature exists to explain the…
News
Oesophageal squamous cell carcinoma (ESCC) is the most common type of oesophageal cancer – a disease that affected more than 600,000 people worldwide last year*. Incidence of the disease varies dramatically around the…
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Surprising discoveries from the Mutographs team challenge the classical view that all carcinogens directly cause mutations and suggest that non-mutagenic agents play a greater role in tumour promotion than originally…